Cheapest GLP-1 Plans Without Insurance (2026)
We compared 12 online GLP-1 clinics — injections and oral pills — so you don't overpay. Real monthly costs, Year 1 totals, and Trustpilot ratings included.
GLP-1 Injections: All Plans Compared (2026)
Compounded semaglutide and tirzepatide injections cost 60–80% less than brand-name Ozempic or Wegovy. Year 1 Cost includes all fees. See ⓘ for dose escalation details.
| Provider | Medication | Monthly Price | Year 1 Cost | Notes | Get Started |
|---|---|---|---|---|---|
| Maximus ★★★★☆4.3 | Semaglutide | $99.99→ $132.99/mo | BEST VALUE$1,464 |
ⓘ$99.99/mo for first 15 weeks, then $132.99/mo. Microdose (0.1mg) at $79.99/mo. Most common dose (1.7mg) at $199.99/mo. |
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| Maximus | Tirzepatide | $132.99→ $165.99/mo | $1,893 |
ⓘ$132.99/mo for first 3 months, then $165.99/mo. Microdose (1mg) at $99.99/mo. Common dose (10mg) at $249.99/mo. |
Get Started → |
| tonik ★★★★☆4.0 | Semaglutide | $149/mo | $1,788 | Get Started → | |
| tonik | Tirzepatide | $229/mo | $2,748 | Get Started → | |
| Gala ★★★★☆4.4 | Comp. Tirzepatide MICRODOSE | $149/mo | $1,788 |
ⓘMicrodose starting price. $179/mo for larger dose. |
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| Gala | Ozempic BRAND NAME | $1,299/mo | $15,588 | Get Started → | |
| MadeMed No Rating | Semaglutide | $139/mo | $1,817 |
ⓘIncl. $149/yr membership. Starts at 0.25mg, up to 2.4mg ($199/mo at max dose). |
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| MadeMed | Tirzepatide | $149/mo | $1,937 |
ⓘIncl. $149/yr membership. Starts at 2.5mg, up to 15mg ($379/mo at max dose). |
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| BreezeMeds No Rating | Comp. Semaglutide | $199/mo | $2,388 | Get Started → | |
| BreezeMeds | Comp. Tirzepatide | $399/mo | $4,788 | Get Started → | |
| Shed ★★★★★4.7 | Comp. Semaglutide | $199/mo | $2,388 |
ⓘStarting dose 0.2mg. |
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| Shed | Wegovy | $274/mo effective | $3,288 |
ⓘ$149/mo medication + $125/mo membership required. |
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| Shed | Comp. Tirzepatide | $299/mo | $3,588 |
ⓘStarting dose 2mg. Also in liquid drops & lozenges from $199/mo. |
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| Shed | Zepbound | $474/mo effective | $5,688 |
ⓘ$349/mo medication + $125/mo membership required. |
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| PeterMD No Rating | Comp. Semaglutide | $139/mo | $1,668 | Get Started → | |
| PeterMD | Comp. Tirzepatide | $149→ $249/mo | $2,888 |
ⓘFirst month $149, then $249/mo. |
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| DirectMeds ★★★★★4.6 | Semaglutide | $297/mo | $3,564 | Get Started → | |
| DirectMeds | Tirzepatide | $399/mo | $4,788 | Get Started → | |
| myrnk No Rating | Tirzepatide | $297/mo | $3,564 | Get Started → | |
| Oak ★★★★★4.6 | Comp. Semaglutide | $183/mo | $2,143 |
ⓘ$50 off first month. All doses one price. |
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| Oak | Comp. Tirzepatide | $250/mo | $2,949 |
ⓘ$50 off first month. All doses one price. |
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| Oak | Mounjaro BRAND NAME | $1,200/mo | $14,400 | Get Started → | |
| Oak | Ozempic BRAND NAME | $1,250/mo | $15,000 | Get Started → | |
| Oak | Zepbound BRAND NAME | $1,350/mo | $16,200 | Get Started → | |
| Oak | Wegovy BRAND NAME | $1,500/mo | $18,000 | Get Started → | |
| enhanceMD ★★★★☆4.2 | Semaglutide | $212/mo | $2,381 |
ⓘ$49 first month. |
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| enhanceMD | Tirzepatide | $280/mo | $3,179 |
ⓘ$99 first month. |
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| Eden Health ★★★★☆4.4 | Comp. Semaglutide | $209/mo | $2,428 |
ⓘ$129 first month. All doses same price. |
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| Eden Health | Comp. Tirzepatide | $329/mo | $3,868 |
ⓘ$249 first month. All doses same price. |
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| TrimRx ★★★☆☆3.3 | Comp. Semaglutide | $179/mo | $2,148 | Get Started → | |
| TrimRx | Comp. Tirzepatide | $259/mo | $3,108 | Get Started → | |
| TrimRx | Ozempic BRAND NAME | $1,149/mo | $13,788 | Get Started → | |
| TrimRx | Mounjaro BRAND NAME | $1,249/mo | $14,988 | Get Started → | |
| TrimRx | Zepbound BRAND NAME | $1,249/mo | $14,988 | Get Started → | |
| TrimRx | Wegovy BRAND NAME | $1,579/mo | $18,948 | Get Started → |
Prices verified April 2026. Year 1 Cost assumes 12 months at starting dose unless otherwise noted. Compounded medications are not FDA-approved. Full disclaimer ↓
GLP-1 Oral Pills: All Plans Compared (2026)
Oral semaglutide and tirzepatide — including Foundayo — are the fastest-growing GLP-1 category in 2026. Ideal for needle-averse patients.
| Provider | Medication | Monthly Price | Year 1 Cost | Notes | Get Started |
|---|---|---|---|---|---|
| Oak ★★★★★4.6 | Wegovy | $100/mo | BEST VALUE$1,200 | Get Started → | |
| Oak | Semaglutide | $245/mo | $2,940 | Get Started → | |
| MadeMed No Rating | Semaglutide | $129/mo | $1,697 |
ⓘIncl. $149/yr membership. Starts at 1mg, up to 6mg ($259/mo at max dose). |
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| MadeMed | Tirzepatide | $189/mo | $2,417 |
ⓘIncl. $149/yr membership. Starts at 3mg, up to 7mg ($299/mo at max dose). |
Get Started → |
| Shed ★★★★★4.7 | Foundayo | $149/mo | $1,788 | Get Started → | |
| BreezeMeds No Rating | Semaglutide | $299/mo | $3,588 | Get Started → | |
| BreezeMeds | Tirzepatide | $399/mo | $4,788 | Get Started → |
Prices verified April 2026. Oral GLP-1 medications require a valid prescription. Full disclaimer ↓
How We Compare GLP-1 Clinics
True Year 1 Cost
We calculate the full 12-month total including membership fees — not just the teaser intro price most clinics advertise.
Trustpilot Ratings
Verified Trustpilot scores are included where available and checked monthly. Clinics without public ratings are marked "No Rating."
Injection & Oral Options
We compare both injectable and oral GLP-1 options across all major compounding and telehealth platforms.
Price Transparency
Prices are sourced directly from clinic websites and audited monthly. We note when dose escalation changes costs.
Affiliate Disclosure: Some links on this page are affiliate links — we may earn a commission if you click through and make a purchase, at no extra cost to you. This supports our free, independent price research. Rankings are based on Year 1 cost, not commission rates.
Compounded vs Brand-Name GLP-1
Brand-name GLP-1s like Ozempic and Zepbound are FDA-approved and cost $1,000–$1,500/month without insurance. Compounded versions contain the same active ingredient, produced by licensed 503B compounding pharmacies, at 60–80% lower cost.
Compounded GLP-1s are legally available while brand-name versions remain on the FDA drug shortage list. Check fda.gov for current shortage status.
Semaglutide vs Tirzepatide
Semaglutide (Ozempic/Wegovy) targets the GLP-1 receptor. Tirzepatide (Zepbound/Mounjaro) targets both GLP-1 and GIP receptors, producing greater average weight loss (~22% vs ~15%) in clinical trials.
Tirzepatide typically costs more than compounded semaglutide. Both require a prescription and dose escalation over several months.
Injection vs Oral GLP-1
Injectable GLP-1s have higher bioavailability and are generally more effective at higher doses. Oral options (Foundayo, compounded oral semaglutide/tirzepatide) are newer and ideal for needle-averse patients.
Studies show oral semaglutide produces 10–15% body weight reduction over 68 weeks — clinically meaningful, though generally less than injections at equivalent doses.
What Is a Microdose GLP-1?
A microdose is a very low starting dose (e.g. 0.1mg semaglutide or 1mg tirzepatide) used to minimize side effects like nausea during the adjustment period. Maximus and Gala both offer microdose programs.
Microdose plans start cheaper ($79.99–$99.99/mo at Maximus) but progress more slowly to therapeutic doses. Best for side-effect-sensitive patients.
Frequently Asked Questions
Maximus offers compounded semaglutide at $99.99/month for the first 15 weeks, then $132.99/month — a Year 1 total of $1,464. tonik and Gala both start at $149/month ($1,788/year).
MadeMed offers oral semaglutide at $129/month plus a $149/year membership — a Year 1 total of $1,697. Shed offers Foundayo at $149/month with no membership ($1,788/year).
Brand-name GLP-1s (Ozempic, Wegovy, Zepbound) are FDA-approved drugs costing $1,000–$1,500/month without insurance. Compounded GLP-1s contain the same active ingredient from licensed 503B pharmacies at 60–80% lower cost. They are not FDA-approved products but are legal while brand-name versions remain on the FDA shortage list.
Semaglutide targets the GLP-1 receptor. Tirzepatide targets both GLP-1 and GIP receptors, producing greater average weight loss (~22% vs ~15%) in clinical trials. Tirzepatide costs more but may deliver stronger results. Both require a prescription and dose escalation over several months.
Yes. All clinics listed require a prescription from a licensed provider. All offer telehealth consultations — you complete a health questionnaire and speak with a clinician digitally. No in-person visit required.
A microdose is a very low starting dose used to minimize nausea. Maximus and Gala offer microdose options from $79.99–$99.99/month. They're cheaper but progress more slowly to therapeutic doses — best for patients sensitive to side effects.
Most patients notice appetite suppression within 2–4 weeks. Meaningful weight loss (5–10%) typically occurs within 3–6 months at therapeutic dose. Clinical trials show 15–22% body weight reduction over 68 weeks.
The clinics on our list are licensed telehealth providers using 503B-registered compounding pharmacies. Compounded GLP-1s are not FDA-approved but are legally produced while brand-name versions are on the FDA shortage list. Verify pharmacy licensure at nabp.pharmacy and always consult your physician first.
⚕ Medical & Legal Disclaimer
Not Medical Advice. AffordableGLPs.com is an independent price comparison site. All content is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a licensed healthcare provider before starting any GLP-1 medication or weight-loss treatment.
Affiliate Disclosure. Some links on this page are affiliate links. We may earn a commission when you purchase through our links, at no additional cost to you. Our rankings are based on Year 1 cost data, not commission rates.
Pricing Accuracy. Prices are audited periodically and may change without notice. Always confirm current pricing on the clinic's website before purchasing. Compounded medications are not FDA-approved products. Legal availability may change as FDA shortage designations are updated — confirm at fda.gov.
Last Price Audit: April 2026