Last Price Audit: April 2026

Cheapest GLP-1 Plans Without Insurance (2026)

We compared 12 online GLP-1 clinics — injections and oral pills — so you don't overpay. Real monthly costs, Year 1 totals, and Trustpilot ratings included.

13 Clinics Compared
$99.99 Lowest Injection/mo
$100 Lowest Oral/mo
42 Plans Compared
  • Prices verified directly from each clinic's website
  • Trustpilot ratings included for verified clinics
  • Affiliate links support this free resource — we may earn a commission

⚕ Not Medical Advice. This site compares prices only. Consult a licensed physician before starting any GLP-1 medication. Full disclaimer ↓

GLP-1 Injections: All Plans Compared (2026)

Compounded semaglutide and tirzepatide injections cost 60–80% less than brand-name Ozempic or Wegovy. Year 1 Cost includes all fees. See ⓘ for dose escalation details.

Provider Medication Monthly Price Year 1 Cost Notes Get Started
Maximus ★★★★☆4.3 Semaglutide $99.99→ $132.99/mo BEST VALUE$1,464
$99.99/mo for first 15 weeks, then $132.99/mo. Microdose (0.1mg) at $79.99/mo. Most common dose (1.7mg) at $199.99/mo.
Get Started →
Maximus Tirzepatide $132.99→ $165.99/mo $1,893
$132.99/mo for first 3 months, then $165.99/mo. Microdose (1mg) at $99.99/mo. Common dose (10mg) at $249.99/mo.
Get Started →
tonik ★★★★☆4.0 Semaglutide $149/mo $1,788 Get Started →
tonik Tirzepatide $229/mo $2,748 Get Started →
Gala ★★★★☆4.4 Comp. Tirzepatide MICRODOSE $149/mo $1,788
Microdose starting price. $179/mo for larger dose.
Get Started →
Gala Ozempic BRAND NAME $1,299/mo $15,588 Get Started →
MadeMed No Rating Semaglutide $139/mo $1,817
Incl. $149/yr membership. Starts at 0.25mg, up to 2.4mg ($199/mo at max dose).
Get Started →
MadeMed Tirzepatide $149/mo $1,937
Incl. $149/yr membership. Starts at 2.5mg, up to 15mg ($379/mo at max dose).
Get Started →
BreezeMeds No Rating Comp. Semaglutide $199/mo $2,388 Get Started →
BreezeMeds Comp. Tirzepatide $399/mo $4,788 Get Started →
Shed ★★★★★4.7 Comp. Semaglutide $199/mo $2,388
Starting dose 0.2mg.
Get Started →
Shed Wegovy $274/mo effective $3,288
$149/mo medication + $125/mo membership required.
Get Started →
Shed Comp. Tirzepatide $299/mo $3,588
Starting dose 2mg. Also in liquid drops & lozenges from $199/mo.
Get Started →
Shed Zepbound $474/mo effective $5,688
$349/mo medication + $125/mo membership required.
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PeterMD No Rating Comp. Semaglutide $139/mo $1,668 Get Started →
PeterMD Comp. Tirzepatide $149→ $249/mo $2,888
First month $149, then $249/mo.
Get Started →
DirectMeds ★★★★★4.6 Semaglutide $297/mo $3,564 Get Started →
DirectMeds Tirzepatide $399/mo $4,788 Get Started →
myrnk No Rating Tirzepatide $297/mo $3,564 Get Started →
Oak ★★★★★4.6 Comp. Semaglutide $183/mo $2,143
$50 off first month. All doses one price.
Get Started →
Oak Comp. Tirzepatide $250/mo $2,949
$50 off first month. All doses one price.
Get Started →
Oak Mounjaro BRAND NAME $1,200/mo $14,400 Get Started →
Oak Ozempic BRAND NAME $1,250/mo $15,000 Get Started →
Oak Zepbound BRAND NAME $1,350/mo $16,200 Get Started →
Oak Wegovy BRAND NAME $1,500/mo $18,000 Get Started →
enhanceMD ★★★★☆4.2 Semaglutide $212/mo $2,381
$49 first month.
Get Started →
enhanceMD Tirzepatide $280/mo $3,179
$99 first month.
Get Started →
Eden Health ★★★★☆4.4 Comp. Semaglutide $209/mo $2,428
$129 first month. All doses same price.
Get Started →
Eden Health Comp. Tirzepatide $329/mo $3,868
$249 first month. All doses same price.
Get Started →
TrimRx ★★★☆☆3.3 Comp. Semaglutide $179/mo $2,148 Get Started →
TrimRx Comp. Tirzepatide $259/mo $3,108 Get Started →
TrimRx Ozempic BRAND NAME $1,149/mo $13,788 Get Started →
TrimRx Mounjaro BRAND NAME $1,249/mo $14,988 Get Started →
TrimRx Zepbound BRAND NAME $1,249/mo $14,988 Get Started →
TrimRx Wegovy BRAND NAME $1,579/mo $18,948 Get Started →

Prices verified April 2026. Year 1 Cost assumes 12 months at starting dose unless otherwise noted. Compounded medications are not FDA-approved. Full disclaimer ↓

GLP-1 Oral Pills: All Plans Compared (2026)

Oral semaglutide and tirzepatide — including Foundayo — are the fastest-growing GLP-1 category in 2026. Ideal for needle-averse patients.

Provider Medication Monthly Price Year 1 Cost Notes Get Started
Oak ★★★★★4.6 Wegovy $100/mo BEST VALUE$1,200 Get Started →
Oak Semaglutide $245/mo $2,940 Get Started →
MadeMed No Rating Semaglutide $129/mo $1,697
Incl. $149/yr membership. Starts at 1mg, up to 6mg ($259/mo at max dose).
Get Started →
MadeMed Tirzepatide $189/mo $2,417
Incl. $149/yr membership. Starts at 3mg, up to 7mg ($299/mo at max dose).
Get Started →
Shed ★★★★★4.7 Foundayo $149/mo $1,788 Get Started →
BreezeMeds No Rating Semaglutide $299/mo $3,588 Get Started →
BreezeMeds Tirzepatide $399/mo $4,788 Get Started →

Prices verified April 2026. Oral GLP-1 medications require a valid prescription. Full disclaimer ↓

How We Compare GLP-1 Clinics

True Year 1 Cost

We calculate the full 12-month total including membership fees — not just the teaser intro price most clinics advertise.

Trustpilot Ratings

Verified Trustpilot scores are included where available and checked monthly. Clinics without public ratings are marked "No Rating."

Injection & Oral Options

We compare both injectable and oral GLP-1 options across all major compounding and telehealth platforms.

Price Transparency

Prices are sourced directly from clinic websites and audited monthly. We note when dose escalation changes costs.

Affiliate Disclosure: Some links on this page are affiliate links — we may earn a commission if you click through and make a purchase, at no extra cost to you. This supports our free, independent price research. Rankings are based on Year 1 cost, not commission rates.

Compounded vs Brand-Name GLP-1

Brand-name GLP-1s like Ozempic and Zepbound are FDA-approved and cost $1,000–$1,500/month without insurance. Compounded versions contain the same active ingredient, produced by licensed 503B compounding pharmacies, at 60–80% lower cost.

Compounded GLP-1s are legally available while brand-name versions remain on the FDA drug shortage list. Check fda.gov for current shortage status.

Semaglutide vs Tirzepatide

Semaglutide (Ozempic/Wegovy) targets the GLP-1 receptor. Tirzepatide (Zepbound/Mounjaro) targets both GLP-1 and GIP receptors, producing greater average weight loss (~22% vs ~15%) in clinical trials.

Tirzepatide typically costs more than compounded semaglutide. Both require a prescription and dose escalation over several months.

Injection vs Oral GLP-1

Injectable GLP-1s have higher bioavailability and are generally more effective at higher doses. Oral options (Foundayo, compounded oral semaglutide/tirzepatide) are newer and ideal for needle-averse patients.

Studies show oral semaglutide produces 10–15% body weight reduction over 68 weeks — clinically meaningful, though generally less than injections at equivalent doses.

What Is a Microdose GLP-1?

A microdose is a very low starting dose (e.g. 0.1mg semaglutide or 1mg tirzepatide) used to minimize side effects like nausea during the adjustment period. Maximus and Gala both offer microdose programs.

Microdose plans start cheaper ($79.99–$99.99/mo at Maximus) but progress more slowly to therapeutic doses. Best for side-effect-sensitive patients.

Frequently Asked Questions

⚕ Medical & Legal Disclaimer

Not Medical Advice. AffordableGLPs.com is an independent price comparison site. All content is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a licensed healthcare provider before starting any GLP-1 medication or weight-loss treatment.

Affiliate Disclosure. Some links on this page are affiliate links. We may earn a commission when you purchase through our links, at no additional cost to you. Our rankings are based on Year 1 cost data, not commission rates.

Pricing Accuracy. Prices are audited periodically and may change without notice. Always confirm current pricing on the clinic's website before purchasing. Compounded medications are not FDA-approved products. Legal availability may change as FDA shortage designations are updated — confirm at fda.gov.

Last Price Audit: April 2026