Cheapest Compounded Semaglutide Without Insurance (2026)
We compared 11 online clinics offering compounded semaglutide injections — real monthly prices, Year 1 totals, and Trustpilot ratings. Starting from $99.99/month.
Compounded Semaglutide Injection Plans — All Clinics (2026)
All clinics below offer compounded semaglutide injections via telehealth. Prices do not require insurance. Year 1 Cost includes all fees at starting dose.
| Provider | Medication | Monthly Price | Year 1 Cost | Notes | Get Started |
|---|---|---|---|---|---|
| Maximus ★★★★☆4.3 | Semaglutide | $99.99→ $132.99/mo | BEST VALUE$1,464 | ⓘ$99.99/mo for first 15 weeks, then $132.99/mo. Microdose (0.1mg) at $79.99/mo. Most common dose (1.7mg) at $199.99/mo. |
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| PeterMD No Rating | Comp. Semaglutide | $139/mo | $1,668 | Get Started → | |
| tonik ★★★★☆4.0 | Semaglutide | $149/mo | $1,788 | Get Started → | |
| MadeMed No Rating | Semaglutide | $139/mo | $1,817 | ⓘIncl. $149/yr membership. Starts at 0.25mg, up to 2.4mg ($199/mo at max dose). |
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| Oak ★★★★★4.6 | Comp. Semaglutide | $183/mo | $2,143 | ⓘ$50 off first month. All doses one price. |
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| enhanceMD ★★★★☆4.2 | Semaglutide | $212/mo | $2,381 | ⓘ$49 first month. |
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| Shed ★★★★★4.7 | Comp. Semaglutide | $199/mo | $2,388 | ⓘStarting dose 0.2mg. |
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| BreezeMeds No Rating | Comp. Semaglutide | $199/mo | $2,388 | Get Started → | |
| Eden Health ★★★★☆4.4 | Comp. Semaglutide | $209/mo | $2,428 | ⓘ$129 first month. All doses same price. |
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| DirectMeds ★★★★★4.6 | Semaglutide | $297/mo | $3,564 | Get Started → | |
| TrimRx ★★★☆☆3.3 | Comp. Semaglutide | $179/mo | $2,148 | Get Started → |
Prices verified April 2026. Year 1 Cost assumes 12 months at starting dose unless otherwise noted. Compounded medications are not FDA-approved. Full disclaimer ↓
What Is Compounded Semaglutide?
Compounded semaglutide contains the same active ingredient as brand-name Ozempic and Wegovy, produced by licensed 503B outsourcing facilities. It costs 60–80% less than brand-name versions.
Compounded GLP-1s are legally available while brand-name versions remain on the FDA shortage list. They are not FDA-approved finished products, but are produced under strict manufacturing standards.
What to Look for in a Clinic
When comparing compounded semaglutide providers, the key factors are Year 1 total cost (including membership fees), dose escalation pricing (some charge more as your dose increases), and Trustpilot rating for patient experience.
Maximus and PeterMD are the cheapest for Year 1. Shed and Oak lead on Trustpilot. Verify pharmacy licensure at nabp.pharmacy before ordering.
Semaglutide Dosing & Titration
Most protocols start at 0.25mg/week and increase every 4 weeks to minimize nausea. Standard therapeutic doses range from 1.0mg to 2.4mg/week. Some clinics (Maximus, Gala) offer microdose programs starting at 0.1mg for sensitive patients.
Clinics with escalating price tiers charge more as your dose increases. Oak and Eden Health offer flat pricing — same price at every dose level.
Telehealth Process
All clinics listed operate as telehealth platforms: no in-person visit required. The process is typically: (1) Complete a health questionnaire online. (2) Telehealth consultation with a licensed clinician. (3) Prescription issued and medication shipped to your door.
Consultations are included in most plans. Some clinics include lab work; others require you to provide recent results.
Compounded Semaglutide: FAQ
Compounded semaglutide is produced by licensed 503B outsourcing facilities under strict FDA manufacturing standards. It contains the same active ingredient as Ozempic and Wegovy. It is not an FDA-approved finished product, but is legally produced while brand-name shortages persist. Always verify pharmacy licensure at nabp.pharmacy and consult your physician before starting.
Ozempic and Wegovy are FDA-approved brand-name products costing $1,000–$1,500/month without insurance. Compounded semaglutide contains the same active ingredient, manufactured at licensed 503B pharmacies, at 60–80% lower cost. Compounded versions are not FDA-approved finished products but are legally produced while brand-name shortages persist — confirmed at fda.gov.
Yes. All clinics listed require a prescription from a licensed provider. All offer telehealth consultations — you complete a health questionnaire and consult with a clinician digitally. No in-person visit required. Consultations are typically included in the monthly plan price.
As of April 2026, Maximus is the cheapest at $99.99/month for the first 15 weeks (then $132.99/month) — a Year 1 total of $1,464. PeterMD is second at a flat $139/month ($1,668/year). Both offer compounded semaglutide injections via telehealth without insurance.
Want tirzepatide or oral GLP-1 options too? See our full 13-clinic comparison including injections and oral pills.
See All GLP-1 Injections + Oral Options →⚕ Medical & Legal Disclaimer
Not Medical Advice. AffordableGLPs.com is an independent price comparison site. All content is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a licensed healthcare provider before starting any GLP-1 medication.
Affiliate Disclosure. Some links on this page are affiliate links. We may earn a commission when you purchase through our links, at no additional cost to you. Rankings are based on Year 1 cost data, not commission rates.
Pricing Accuracy. Prices are audited periodically and may change without notice. Always confirm current pricing on the clinic's website before purchasing. Compounded medications are not FDA-approved products.
Last Price Audit: April 2026